GGT may be measured along with other tests (such as the ALT, AST, ALP, and bilirubin tests) to differentiate between liver or bile duct disorders and bone disease. I am glad you were able to catch this abnormality on routine lab work. Hi Amy, GGT is an enzyme associated with the membranes of cells from the bile ducts, as well as the membranes of cells from the pancreas and kidneys. This test measures protein and electrolyte levels. Glucose is blood sugar. We adopted our dog about 2.5 years ago when she was about 3 years old from our local humane society. He had no other symptoms. When dealing with eye issues, time is always of the essence. I hope you can get some answers quickly and start the appropriate treatment plan to give your pup the best quality of life. I feel like you are on the right track with the diagnostics that have already been performed. There is really no way to know for sure without a definitive diagnosis. They also did an ultrasound of the bladder and a urine analysis. WebIt is a marker of intrahepatic (eg, feline hepatic lipidosis) or extrahepatic (eg, bile duct obstruction) cholestasis. She should be able to spot any ongoing trends that could be helped with additional holistic support. Since I havent examined your dog myself, I cant make specific conclusions or recommendations. She also has an odd occasional cough. Latanaprost, NeoPolyDex, and Dorzolimide. Clinical Biochemistry. cancer of bile ducts), Gastroenteritis (I.e. What do I do now? They are going to do a 12 hour fasting test in 3 weeks. Those 10 days were AWFUL. Sometime being presented with all the different diagnostic options can feel a bit overwhelming. I have to admit I do not have much personal experience with treating this condition and cant give you advice on if the Propafenone is a good idea. Blood Clotting Times: We test your dog's blood for bleeding disorders. It is never wrong to voice your opinion and ask questions until you are comfortable with how things are proceeding. Required fields are marked *. An ultrasound can evaluate for masses or nodules in the liver and can also assess the gallbladder for signs of infection, gallstones, or a mucocele. Aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALKP), gamma glutamyl transferase (GGT), and total bilirubin (TBIL) are liver enzymes measured on the blood chemistry. I feel like the New Zealand deer antler velvet is such a game changer and isnt found in any of the other supplements you currently use. Dexter is lucky to have you advocating for his health and wellbeing. I will repeat her bloodwork in a month or two when the weather cools. Report / Delete 1 Reply. Our dog also went from 24 pounds in July to 17.4 pounds in January (her ideal weight). The way things looked last night I felt like she might need to be euthanized. However, conditions that cause ongoing damage to the bones, such as bone cancer (i.e. RBC 8.86 5.39 8.70 M/L H Hx of EVERYTHING THAT CAN GO WRONG DOES GO WRONG as he is an ER and specialty RVTs dog typical. And just because the ALP is high doesnt tell you if the underlying cause is life threatening or rather benign. Alanine It is not a bad idea to pursue further testing. anaphylaxis for no reason we could find, ruptured ear drums, foxtails, pneumonia, torn and repaired ACLs, allergies.the works. Make sure your veterinarian compares these results to your dogs young adult values. This enzyme increases in post-hepatic biliary obstruction and can reach 5 to 30 times normal. Explore the Top 10 Reasons, Dog Overheating? GGT is a liver enzyme. Without playing a personal role in your dogs medical care it is hard to make specific conclusions. Please be sure to tell them you are suspicious Teddy may be in some pain. There are additional ways to check liver function such as more advanced blood testing and ultrasound. I havent had any other tests done on him but I am wondering if it has to do with Cushings Disease because he has a pot bellied appearance. Hi Ashley, I am curious to know what the results will be. I hope you can find the answers you need to help your senior girl continue living her best life. He was drinking LOADS of water and had a voracious appetite(always been very food motivated tho). If you dont see the improvements you are hoping for, I think the ultrasound investigation sounds like a very good next step. Liver And Bile (Hepatobiliary) Disease. We are doing an ultrasound next week but I cant help but worry it will uncover something bad. The content on this website is not meant to replace veterinary advice. I would not be worried about the sedation for the ultrasound. DNM RECOMMENDS: Maintain your dogs overall health with Four Leaf Rovers Protect, a daily soil-based probiotic that supports the immune system and helps remove toxins. I am sorry your Great Dane is struggling with chronic V. Tach. In dogs, hepatic GGT is located on the hepatocyte canalicular membrane. Reading these other posts have been helpful. She has no redness or anything on her skin but its almost like OCD. It was over 1000. I was told to wait a year and see if had changed. Alkaline Phosphatases normal job in the body is complicated, and actually isnt critical to understand here. Dr. Julie Buzby January 6, 2022 92 Comments Share Finding out your senior dogs blood work showed a high ALP can be confusing and concerning. Hi Joan, Even more specifically, it is associated with the liver cells that line the bile ducts. [more]. Shes been on Denamarin for about six months now and her ALP remains high, despite a deep dental clean and more than 5 pounds weight loss, so her doctor is recommending an ultrasound so shell have a better sense of what might be happening so she can recommend next steps. Gamma-glutamyltransferase. Obviously I do not know if this is true in your case but gall stones are likely to change the other tests as well while pancreatic cancer is much less common! Dr. Buzbys ToeGripsinstant traction for senior and special needs dogs who struggle to walk on slippery floors. This way you get plenty of one on one even if it has to be over the phone. They give a quick picture of whats happening at the moment the test is done. The three most important forms are ALP from the liver (L-ALP), ALP made in the bone (B-ALP), and ALP that is released in response to excess levels of corticosteroids (C-ALP). Praying for a positive outcome. The chemistry panel should be the one that the most convenient veterinary diagnostic laboratory uses as their normal panel. Structural problems that block the flow of bile out of the liver, into the gallbladder, or from the gallbladder into the intestinal tract, can also cause a high ALP in dogs. Try not to worry yourself too much in the meantime. My doogy son teddy is somewhere between 11 and 13. Luckily my 10 yr old (almost 11yr old) cocker spaniel doesnt have the other levels high. She recently started not eating her dry food she eats it and then spits it out, so we switched to canned food (prescription). He has been fully grown for a few months now. Finally the detox was over and we started the Galliprant (100mg, 1x/day) and he has regained decent mobility, but not as good as on rimadyl.. We repeated a blood test in June 2022 and those ALPs were still elevated. Id do anything for my dog. Home > Vaccination > Handy Guide To Dog Blood Tests. Learn more. WebA gamma-glutamyl transferase (GGT) blood test measures the activity of GGT in your blood. There are also tests designed to evaluate specific organs or organ systems. I have a hunch that this is just going to be a blip on the radar for good old Sampson, and that the local squirrels wont be able to rest anytime soon. Hello. I am sorry your senior guy is having issues with elevated liver enzymes. If blood work is rechecked a few weeks after the dental procedure, you may find these levels have improved just from treating the dental issues. I have a 10 yr old Great Dane that has severe v. tach. I would not be overly worried about the UTI at this point. Wishing you both the best and praying for a clear path forward. Be the first to know about the latest senior dog health care tips from Dr. Buzby, Does he need to be on Denamarin? as he has a history of pancreatitis. He had a senior blood panel and everything was good but ASP was 818. June 2016. Bile is then released from the gallbladder into the GI tract where it helps with digestion. I hope the ultrasound findings will offer you some answers and guide you in the treatment process. After weighing the pros and cons, Sarah decided to continue monitoring for now. Higher doses of steroids, such as those used for immunosuppression in cases of IMHA in dogs or other immune-mediated conditions, tend to cause higher ALP elevations. He was only on rimadyl for 2 weeks before the bad liver results, and it was like the denamarin was making him worse which is ridiculous of course (milk thistle cant hurt anyone). It can be difficult to find a cause without investigating further and doing some additional testing. Dr. Julie Buzby January 6, 2022 94 Comments. I wish you and your sweet girl the best. Shes already on proin for her spay incontinence for past 2 years or so. He is clinically healthy and not showing any signs of not feeling good. I understand your concern about these liver changes and decreased appetite in your little pup. He has year round allergies, is overweight at 18 pounds, and is on 5.4 apoquel and cytopoint shots every 3 weeks. .. vet wants to test for cushings . I am praying that the ultrasound on Thursday reveals positive results and a treatment plan can be started. Her remaining liver function tests, albumin, bilirubin, glucose levels, creatinine, and CBC were all normal, but Im very worried about her blood work. Vet started a course of adequan injections, but I didnt see any difference after 7 months so we d/c. Yesterday, Aug. 16, we had more bloodwork done and her ALKP had jumped to 1783 U/L and is quite significant. High levels of GGT are a sign of liver damage. Wishing you the best of luck! Together, you can tackle whatever the future brings and keep making memories in the process. She has a very large fat lump which she was booked in for surgery in June to get removed along with another smaller lump which is growing rather rapidly (it is affecting her balance and soon it will affect her mobility). But at the end of the day, you and your trusted vet should be able to work together to create a plan for your dogbe it a watchful waiting approach or further diagnosticsthat you feel confident about. That will be done this weekend. I am sorry Cocos ALP is still elevated despite the SAMe supplement you have been giving. His teeth werent great in September but he now has severe dental disease, which could explain the spike from 322 to 800. GGT can't diagnose the cause of liver damage, so it's usually done with other liver tests. A CBC gives information on hydration status, anaemia, infection, the bloods clotting ability, and the ability of the immune system to respond. I understand your concerns with this elevated liver enzyme found on your dogs lab work. After a level of 571 vet recommended milk thistle, and he had a recheck and remained elevated (slightly more so into the 600 level for ALKP). However, unlike ALP, GGT is not elevated with increased osteoblastic activity (e.g., growing dogs) and may not be elevated in dogs on anticonvulsant medication. complete blood count), full chemistry panel (if the ALP elevation was found on a short panel), T4 level, and urinalysis. That was how we found that Sampsons ALP, while normal on his last yearly bloodwork, was now moderately high. I am glad your vet has scheduled an ultrasound and would be very curious to find out the results. Since she had finished the SAMeLQ 225 tablets, I asked to have the ALP rechecked. Glucose is increased in dogs and cats with diabetes mellitus. Today I took my Coco in for her yearly shots. Hi Katie, My 9 year old Boston Terrier was shedding a whole bunch more than Id ever noticed. Please, how would you explain these elevations, and how would you proceed? He had geriatric blood work done and it was Overall good but his ALP, was at 537 in August 2022 and now has increased to 1699. Webgamma-Glutamyltransferase (GGT) activity in canine kidney, pancreas, and liver is similar to previously reported values for other species. This is especially true of cats. All the best. So dogs fed a raw meat diet will often have higher BUN. Thank you in advance. She has degenerative heart valve syndrome, a grade 3 heart murmur and has been on vetmedin 1.25mg for the last 6 months for that. From my point of view, more information is always better. BEST SELLER! If your dog has elevated bile acid levels, your veterinarian will likely recommend additional testing or referral to an internal medicine specialist. Hi Kelly, Any ideas or suggestions would be helpful. Youll want to ask your vet for help in understanding dog blood test results. She has no other symptoms at all. Shes almost six, is a mixed breed, and has lots of energy. You are correct that prednisone can cause these liver values to increase more depending on the situation. However, if there is not an obvious reason for the high ALP (like taking a course of steroids), then your veterinarian may use the degree of elevation to help decide how aggressive to be with additional diagnostic testing. My best recommendation would be to schedule a consult with an internal medicine specialist. Earlier we touched on the fact that the liver makes alkaline phosphatase (ALP), but other places in the body make it too. She had a liver ultrasound and it was enlarged but showed no masses. The high APL came out of nowhere.
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